Allergic reactions are possible, ranging from skin manifestations (purpura, dermatitis, pruritus, erythema) and up to anaphylactic shock. There are rare violations from the blood: leukopenia, eosinophilia, hemolytic changes, agranulocytosis, thrombocytopenia. In low-dose or premature babies, the use of Lasix in the first weeks of life can lead to the non-extinction of the Botallov duct. Contraindications Contraindications are severe electrolyte imbalance, intolerance to furosemide or any other component of Lasix, anuria, dehydration, BCC deficiency, hepatic coma of any stage, pregnancy up to 12 weeks and lactation. Lasix in http://canadaslim.net/buy-lasix/ is a high-speed diuretic, which is a sulfonamide derivative. Lasix blocks the transport system of Na +, K +, Cl - ions in the thick segment of the ascending knee of the Henle loop, and therefore, its saluretic effect depends on the drug delivery to the lumen of the renal tubules (due to the mechanism of anion transport). The diuretic effect of the drug Lasix is associated with the inhibition of the reabsorption of sodium chloride in this section of the Henle loop. Secondary effects on the increase in sodium excretion are: an increase in the amount of urine released (due to osmotically bound water) and an increase in the secretion of potassium in the distal part of the renal tubule. At the same time, the excretion of calcium and magnesium ions increases. With the repeated administration of the drug Lasix, its diuretic activity does not decrease, as the drug interrupts the tubular-glomerular feedback in Macula densa (tubular structure closely related to the juxtaglomerular complex). Lasix causes dose-dependent stimulation of the renin-angiotensin-aldosterone system.